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Melphalan is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Melphalan is used to treat multiple myeloma (a type of blood cancer) and cancer of the ovary.
Melphalan treats only the symptoms of ovarian cancer or multiple myeloma, but does not treat the cancer itself.
Important Information
Melphalan can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches).
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You should not use melphalan if you are allergic to it, or if prior treatment with this medication was unsuccessful in controlling your disease.
To make sure melphalan is safe for you, tell your doctor if you have:
- a weak immune system (caused by disease or by using certain medicine);
- liver disease;
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- a history of chemotherapy or radiation.
Using melphalan may increase your risk of developing other types of cancer, such as leukemia. Ask your doctor about your specific risk.
Do not use melphalan if you are pregnant. It could harm the unborn baby. Use effective birth control to avoid pregnancy during your treatment with melphalan. Follow your doctor's instructions about how long to prevent pregnancy after your treatment ends.
This medication may affect fertility (your ability to have children), whether you are a man or a woman.
It is not known whether melphalan passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using melphalan.
How is melphalan given?
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take Alkeran in larger or smaller amounts or for longer than recommended.
Oral melphalan is a tablet you take by mouth. Injectable melphalan is injected into a vein through an IV. A healthcare provider will give you this injection.
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using melphalan.
Melphalan can lower blood cells that help your body fight infections and help your blood to clot. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often.
Store melphalan tablets in the refrigerator and protect them from light.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Call your doctor for instructions if you miss an appointment for your melphalan injection.
What should I avoid while taking melphalan?
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
Do not receive a "live" vaccine while using melphalan. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.
melphalan can pass into body fluids (urine, feces, vomit). Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.
Melphalan side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
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Common side effects may include:
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Jane, I had given up hope of seeing it, but your renderings make me want to try tomorrow night. Don
Saw it naked eye tonight, moon above tomorrow!!
I tried, unsucessfully, to see it last night with my three boys (ages 6, 9 and 10 1/2). We still had fun messing around with dry ice and talking about what comets are. We’ll try to see it again tonight. Thanks for your drawings and description, Jane. It’s very helpful to me as I try to find it.
I’ll add a few images to the bottom of this same blog. Moon and comet last night (Tues the 12th) – and I was able to see the comet with my unaided eye 5+ defrees to the left of the moon. Followed the “horn” aka the tips of the Cheshire cat moon smile in a straight line, and there was the comet!!
[...] with difficulty just after sunset, low in the western sky. I’ve seen it myself through binoculars and with my own eyes! It is still be visible without a telescope, binoculars will help pull it out [...]